Nestled on approximately 1.5 acres of pristine Kiawah Island landscape, 108 Salthouse Lane is a private sanctuary offering an unparalleled blend of seclusion and panoramic beauty. Designed by Charleston architect Zach Carney and brough to life by renowned Buffington Homes, its slate roof and cedar shake siding harmonize perfectly with the natural surroundings. This one-owner residence is thoughtfully integrated into its environment, boasting breathtaking, unobstructed views of the Kiawah River and marsh, with a picturesque glimpse of The River Courses 17th hole. An expansive deck with frameless glass railings invites you to immerse yourself in the ever-changing Lowcountry scenery. Designed for both intimate living and grand entertaining, this exceptional compound features a main residence with attached and detached guest houses, providing ample space for family and friends. The residence is truly unique in its ability to offer both intimacy for everyday living and ample space to host family and friends in an unforgettable setting. Outdoor living is elevated with a shared, private deep-water dock ideal for exploring the river, as well as an oversized infinity-edge pool with a summer kitchen and pool bathroom, creating a true outdoor oasis. A screened porch complete with a fireplace and stone spa, extends enjoyment into every season. The main residence showcases architectural elegance with transom-topped, oversized windows and French doors, and a spacious great room featuring a gas-log fireplace, coffered ceilings and sweeping views. A gourmet kitchen, butlers pantry, and elegant dining room cater to sophisticated entertaining. The main level also includes a luxurious primary suite, while upstairs provides four ensuite bedrooms, one of which opens to a private balcony with breathtaking river views, a well-appointed bunkroom, a loft sitting area, and an office. Designed for both convenience and accessibility, the home includes two elevators, a three-car garage and plenty of under home storage for bikes and beach gear. Additional features include covered walkways, multiple open decks, and premium exterior finishes that blend durability with timeless coastal charm. Located in The Settlement at Kiawah Island, this home includes access to the exclusive Kiawah Island Club, offering championship golf, tennis, a deluxe spa, an oceanfront beach club, fine dining, and a calendar of exclusive social events. 108 Salthouse Lane is more than a home, its a retreat where luxury meets nature, offering an exceptional lifestyle on Kiawah Island. Kiawah Island Club Membership (Sports) is a condition of purchase.